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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ffe027e7355c6f16484c9db44ca3a43e77bb1ea58221ab5f5d9d8a12ef3423c' 
  AND token = 'k2zku3F4VI/EKddVCVZuwaUcZEUcXltz2k+IxoUhfP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}