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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac8207ca331ec4766ceef6c1cf8a5de0f76f61f6285f39bfae555ebc8df3170c' 
  AND token = '00YnIefv42Y4s6WPwt/K0mdFOLvoPqoo+ZRzc5/oXVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}