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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0abc77457161ff0c3467d410510a9e23be27342aad88dd36e0ae6fd7ad5745' 
  AND token = 'dmqKeLRbfNpL45gcJZl5t0tR52E/zfeSV6T8wGnbwSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}