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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e78e056a0a9175ff979566fd09e527f9cd2e0e61c2459e15d4b49005c2f8ce1' 
  AND token = 'pPtdcUBv+a2zKZjAQRZawdHcKKMbmJVFE9OkEYZcui4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}