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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b40b8d99d9c7e4471d384c5033a05a0897be618219418216e81a16b9e82fc8' 
  AND token = 'u3iBLrZw1xdvAFTwgFnP9AAN/FlIHGwpKZLIsvWlZbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}