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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d59f728a5766ce2500dedc101f7a3aa3fbdc6dd0fb4696c5d361bb698dfadc' 
  AND token = 'nob/rn5Wr60itHJZGIl+Xv+Si0G4bNhtu90JXHYmKLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}