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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2546216703b8a11e5d01d7a974d77450b337a7501b48ac82d3ec0f6cdcbcb108' 
  AND token = 'hIssKmXtFqR2AEun2AigUxC/zHpR/WcDwZcNAhxrqNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}