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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c7344904f38adf902e246f667d527f6ba3d1dc8908dd2ae6c2e4a01292e9f3' 
  AND token = 'eqwaQ1Rtub9T55HKdIk94uNFeMTszsw6eYEY9MVSdKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}