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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22030aabf1a1881bfc77c567633cfad4ed22da79fa273dbbfb874f68a122b065' 
  AND token = 'uw9p7NrlBW9hqnkGcL1nv0m7zUbH5euy5GN6eayA/L8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}