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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da6863118a157e7f26da135d4c548374921ade5337f16b3390bc99e75f24f103' 
  AND token = '3YzCx41OYPL49EfTnpnXPI9mzpZSxGM6n6tmWVLWM4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}