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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9f81b6ab81ab17abf4b3eb9d59f5c9c614dd1815480fa318bb83e5befd6c793' 
  AND token = '+rFKV6HBWbSKitZxx7gI7yAyKRKd5UFYmOlxxQVvdng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}