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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4d09454ece0db64a05077e79b43cb86deddc9f24566a9c5387d77d2890429da' 
  AND token = '0ZgOgVfXCEaGaX1mBayZUr9v5EijQ6kqAnPQR03HUDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}