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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a9e2a6a71fe5f9a6b47509508371a9fbd2d0b11595a2581f2888ce78b0e505' 
  AND token = '/EOImGX7lbOv0xUGqxogepYymnpXuZQCs9n0kqOAaL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}