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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf79900628306c1eeee5ed12f32072644c41483f49e5fe825da8afb3e0b08545' 
  AND token = 'xfDNPhpOddiQi7++ZV4m8vQjyGbqN0Z2edvC60W5tzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}