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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5a9cd60566fc681b06260a48dd568787a26aac3e58f768d05e077397cc00f7' 
  AND token = 'QrfuipUonqZIHf8Rrl6o4hxLYLPpKdVc8lo7vMtKJsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}