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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25508ee5219fd0d897da1c2bf98df6059e018c61b4b859b6d4ecea20e6266c4f' 
  AND token = 'BEQ9ZZ9sWmDs+X5lGbkXsEK45CmWaYLopc0R/GKYt1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}