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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17bf53619264a3266c7aeef0e7dc55342978653990b9964a39f9b7f81f9a62b1' 
  AND token = '6X31vPl00Mgqy51AbsuumCR9/on2wCiiR9G1sUklIKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}