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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aedbcb6d7e2d351f3efba81bdd9da2431ee38a9a7f3b9109e7cd7f0a460f927' 
  AND token = '37Uq3U9fdPcUTXdPHt3vWmK1iAKq6BxXReyHd4gFVMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}