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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52785e2082e9eb0cc419701b4977cdf030af311da2453b790cf2e7ed87040a57' 
  AND token = 'e7ZJF/L+mBmyQlVaVcJ0YdOUYP5p7xqvqHBbm2KVL9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}