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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e05fd6907e9a8e7fb9db5a27e062fbf7a0dd7c6f23441d9a306ff20d6b1dd5d' 
  AND token = 'VZkpNofoUEICkMt7S+OYmWxTrVjUXoWkxj1SSd14X7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}