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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd64119f39a77f033b66433aed7259b1627d305d8af1e9318b9639edbe59d0e55' 
  AND token = 'j44e0hxRMztypUzL5eDQTVXliny5qInwpDa5bB0CVeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}