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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3639eff5af0aa862eb8063b65b81276a5d2a8a7917831bf1c9e6ded64f328763' 
  AND token = 'eUr6QI/641NVU8BYmCNq6kkj/7mNaB4+ayQOnPEU3ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}