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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a287f3f429c5cf364f194b5121c5f57131268cf79d08482bbb280a1f40a399' 
  AND token = 'PkQGdMbkcNdxy6ZAFup+IPqf3Vb2mbSYR86k/GDzdgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}