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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4ca8f64176d7bf3850ee794253a42db7f187bd956af5e6a1631dbd714e0594f' 
  AND token = '0PepC43EOGI5k/eE/0vJ6TTzsx+n9KdCziJ9BM+HjyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}