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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ae9c7920bc9a70dbe2257c73cdd3b0058b2eae9b29afb5912f70b929122a79' 
  AND token = 'HYX9qwcQEx9d33m/LVRPdIsaqDr1pPBWfc0ldj08gjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}