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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a04d4372bbb9a1367ae180ad3621445eafc92f7842e4f32ef18967a46dcea3' 
  AND token = '3H5ptSichfIXzXy8SXJ2n7PXZ4SywcJ5IU6PwkUt0So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}