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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7801da6e431fc76ba2a81f223fb2d5fe53e3681ed028b2640dee5177fcee7b37' 
  AND token = 'TCxGkB1352ec4pMVlufQxusQd3HgD2/enMr8qq9IWe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}