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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309950369f22f6f662fba3e42a3c8e6f69ed71ae68d2c6555255a14fa8866660' 
  AND token = 'OzQg0/zIiab9oOk7/PLAsIPvdGUD5lKUmm1sXQtNyWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}