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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b4588bc3edf904f6ea4d2875ed5229ddb090d179a704409ccd873a4bef4f449' 
  AND token = 'jA8F4R4OIQS9fEsCeZJsPD14s/K5RjynZVJ8j9avXGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}