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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3c50426d0c11d75a754fdd0191ddc31a223f101139a6573e5f3a8477c761f1' 
  AND token = '2BVi/vcKuqtRPC7ya531N3TezO4q6y5h/ZDVYLfqQ5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}