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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13363ad1965d6409f4df3a23f37dba00f3ab4b75328eb95f0ed83b0d5111bad0' 
  AND token = 'eImaymOtdBwgbOf0spYHr3dMN3WcW8AiDlceaMNFe40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}