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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e02e2a276b6e225a7d01552e5228ab2e5c3fbd9c74126db7f79fe76ae5fec6a2' 
  AND token = 'RDoU9UU1PDn2pPfAmWECjzPFS1xdQC8/m4HI9S14uMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}