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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af561e449869954aa4c9457053b101249344f50f8c6c6496835e92622280d51f' 
  AND token = '/0VsvjrLJm+GLyoZGTt1m9GIWd8G+xzI7Gz++I9xlRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}