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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666ed1ddae35091b5dfa4c12f09ca7a528c943ed01c34dd7bc550a786f1ec127' 
  AND token = 'pO+dXzAjL1CMtkJopl0Yh0SRdxQZy4BAD2x6DfxscMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}