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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7626b6f8ed6e540ecbd1c698a13763e1084a0024986da9d7f7cb6349e2d5706a' 
  AND token = 'rX2VYKXXC8GCt9bH++b6R/sP2+R7GNaU4x8Xj9WX6Fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}