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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0759885f14549b9caa1a65b846678652a639cde1944d8fe493808815c63357ce' 
  AND token = 'eQUaNUOiFq1F0EDyO6CSGfOE47Lxs2NUyrMZLQ3JXb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}