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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ab1fd51e57e86a48b37aa994d7434c7b0b97c6a1480fb117c09bf3a8778af18' 
  AND token = 'DmS3NitVRjO87vjBCxfQB+mHqBAmtgtGN1bxRCkj6Es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}