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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c352bb452b4e677e41f38aa172176e912d192424eb56da00931f1f4acc1b7be6' 
  AND token = 'B3Q8AtJJ1M4gto7CvCxRTWPCG6hHfspRcHz3t1Hp484=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}