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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '904c0c7ee6f438d52e3bdf2018c5a847aacec12150ec8c6e99664fd7129b024d' 
  AND token = 'ZJOd0I/nFoo6iB/SSFof1EBgBOFerWWxl9tJXTDNf9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}