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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bcf29885f95bf5d4c5295cbd5f6bfd53bc3c954c3f872bd66508a01f6650448' 
  AND token = 'RNGRAtuWO+GicoJJgXTt7CeaXibi5etL6bhfUnRjJoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}