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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3163b001f43c8adfe88ea4640441d2407fb8009e630b29ea3f19cdc6a4e63388' 
  AND token = 'A6bEsfAbQR6wtJlDS84wXzDk7PVSxzz/fqLR52YcQ2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}