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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f9a4dd1f46636bc24a3a0a9dfaecafe9368be37c0f1afbe0606dd5ce2bfd822' 
  AND token = 'ZfoN+OO4fKESwvZHyiYBAiAWpT5AHUXLQMO6AIwovxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}