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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6667091bb3faffd61d0a25d087435f5ba27be3ef1203b48dbec13c599d8afc8e' 
  AND token = 'bZYphG5hUWRpP8ReweCf0vo4T1a3adGdBjgQw9xOPOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}