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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330efc189d503e5d31ac744cf8e0737c520d6162b1b9416909a184f4c8fb0344' 
  AND token = '9DMEO4w3vIfAXRZlGk3Ak02Ddpbp2Q2Q4EeD9ERmHjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}