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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b456a02cec8f83d6274030f234100b06af37184e6be64f458ac388f276df0e9b' 
  AND token = '5oYvgIC6CdMd1ysUPiLNL3VtBjxSd9z5fiHGD/BEYpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}