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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8083e3f7778e3ff7294bb3369c942b2d572000c92ed69016e96f6ee76f1c2eb0' 
  AND token = 'Zm/ntwsanCAWlB0Ori7dHlRuM7AnERiKOi3zgDb0Kd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}