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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b39892e2077ec3f27951880cf1897716aced611c607d00a12018b5406a82144' 
  AND token = 'O3Q0X+pDhI9QwZGAC7fkuEhynvcoC6/wGLMKuYS8tTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}