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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97aaf3f33b7f175c4f3f09033b88496f1bb2469d8aad76911da896c4c8eaa17' 
  AND token = 'Dv34rOM8XjT+wvpIY4rbUBHsqwRx6cBhjAQEfYXMsvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}