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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b13146a9c2cef0df9e1f949d4e5691ca0a7b8febd94d806651c3d354752ac81b' 
  AND token = 'v2fBJ0fCX3zBUmv32cNd0lwaNMjeHAw0qCyK0Xc7Tek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}