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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6c5e0a095b769fc05241415cbee9fb0dbcecffb82685d88556219f848e6605' 
  AND token = '0f6351WCvqvgWqm81CrtGebvY4o5d/Agxn9qqN26xJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}